Sortilin: Antibodies
Sortilin is a type I transmembrane glycoprotein that is one of five known members of the mammalian vacuolar protein sorting 10p domain (Vps10p-D) family of sorting receptors. During murine development, sortilin is mainly expressed in the nervous system where it is a receptor for neuropeptides including neurotensin, NGF, and BDNF. Pro-NGF (or the NGF propeptide alone) binds Sortilin with much higher affinity than does mature NGF. Pro-NGF binding to the receptor complex of Sortilin and the NGF Receptor/p75NTR may result in the induction of apoptosis.
13 results for "Sortilin Primary Antibodies" in Products
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Sortilin: Antibodies
Sortilin is a type I transmembrane glycoprotein that is one of five known members of the mammalian vacuolar protein sorting 10p domain (Vps10p-D) family of sorting receptors. During murine development, sortilin is mainly expressed in the nervous system where it is a receptor for neuropeptides including neurotensin, NGF, and BDNF. Pro-NGF (or the NGF propeptide alone) binds Sortilin with much higher affinity than does mature NGF. Pro-NGF binding to the receptor complex of Sortilin and the NGF Receptor/p75NTR may result in the induction of apoptosis.
13 results for "Sortilin Primary Antibodies" in Products
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Immunohistochemistry, Simple Western, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Flow Cytometry, Immunohistochemistry, Simple Western, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #334703 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #334708 |
Applications : | Knockout Validated, Simple Western, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #334703 |
Applications : | CyTOF-ready, Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #334703 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #334703 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #334703 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #334703 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #334703 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #334703 |
Applications : | Flow Cytometry |