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Sortilin Products

Sortilin is a type I transmembrane glycoprotein that is one of five known members of the mammalian vacuolar protein sorting 10p domain (Vps10p-D) family of sorting receptors. During murine development, sortilin is mainly expressed in the nervous system where it is a receptor for neuropeptides including neurotensin, NGF, and BDNF. Pro-NGF (or the NGF propeptide alone) binds Sortilin with much higher affinity than does mature NGF. Pro-NGF binding to the receptor complex of Sortilin and the NGF Receptor/p75NTR may result in the induction of apoptosis.

15 results for "Sortilin" in Products

Sortilin Products

Sortilin is a type I transmembrane glycoprotein that is one of five known members of the mammalian vacuolar protein sorting 10p domain (Vps10p-D) family of sorting receptors. During murine development, sortilin is mainly expressed in the nervous system where it is a receptor for neuropeptides including neurotensin, NGF, and BDNF. Pro-NGF (or the NGF propeptide alone) binds Sortilin with much higher affinity than does mature NGF. Pro-NGF binding to the receptor complex of Sortilin and the NGF Receptor/p75NTR may result in the induction of apoptosis.

15 results for "Sortilin" in Products

Flow, CyTOF-ready
WB, Simple Western, IHC, Block
Catalog #: 2934-ST
Bind
WB
WB, Simple Western, Flow, IHC, Block
WB, Simple Western, KO
Catalog #: FAB31541G
Flow
Catalog #: FAB31541R
Flow
Catalog #: FAB31541S
Flow
Catalog #: FAB31541T
Flow
WB
Catalog #: FAB31541V
Flow
Catalog #: FAB31541U
Flow
Catalog #: FAB31541N
Flow
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