R-Spondin 1 Products
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
232 results for "R-Spondin 1" in Products
232 results for "R-Spondin 1" in Products
R-Spondin 1 Products
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
| Source: | CHO |
| Accession #: | Q2MKA7 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | NP_619624 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2B Monoclonal Clone #422407 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | B/N |
![R-Spondin 1 Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/af4645cl1_sheep-r-spondin-1-pab-corafluor-1-12920251455494.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #852010 |
| Applications: | B/N |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![R-Spondin 1 Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp1-77354cl1_rabbit-r-spondin-1-pab-corafluor-1-892025153290.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
![R-Spondin 1 Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/af3474cl1_goat-r-spondin-1-pab-corafluor-1-109202511303223.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | IHC, WB |
| Source: | E. coli |
| Accession #: | Q9Z132 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Monoclonal Clone #422407 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | IHC, WB |
![Western Blot: R-Spondin 1 Antibody (OTI11A9) [NBP2-45636]](https://resources.bio-techne.com/images/products/R-Spondin-1-Antibody-11A9-Western-Blot-NBP2-45636-img0002.jpg "Western Blot: R-Spondin 1 Antibody (OTI11A9) [NBP2-45636]")
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
Biotinylated
| Source: | CHO |
| Accession #: | Q2MKA7.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q2MKA7.1 |
| Applications: | BA |
| Source: | CHO |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #852010 |
| Applications: | Neut |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Monoclonal Clone #422407 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Monoclonal Clone #422407 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |