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309 results for "PTEN" in Products

PTEN Products

The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10), also known as MMAC1 (mutated in multiple advanced cancers 1), encodes a phosphatase that contains the catalytic signature motif (HCXXGXXRS/T) found in all members of the protein tyrosine phosphatase family. In vitro, the recombinant PTEN has both lipid phosphatase and protein phosphatase activities. In vivo, the importance of PTEN catalytic activity in its tumor suppressor functions is underscored by the fact that the majority of PTEN missense mutations detected in tumor specimens target the phosphatase domain and cause a loss in PTEN phosphatase activity.

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #7O6F4
Applications: WB, ELISA, ICC/IF, IP, KO
Western Blot: PTEN Antibody (7O6F4) [NBP3-15666]
(5)
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #CL11722
Applications: IHC, WB
Immunohistochemistry-Paraffin: PTEN Antibody [NBP3-21200] -
(7)
Reactivity: Human
Details: Mouse IgG2A Monoclonal Clone #CL11723
Applications: IHC, WB
Western Blot: PTEN Antibody [NBP3-21201] -
(7)
Source: E. coli
Accession #: P60484
Applications: InhibAct
R&D Systems Recombinant Proteins and Enzymes
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