PTEN Products
The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10), also known as MMAC1 (mutated in multiple advanced cancers 1), encodes a phosphatase that contains the catalytic signature motif (HCXXGXXRS/T) found in all members of the protein tyrosine phosphatase family. In vitro, the recombinant PTEN has both lipid phosphatase and protein phosphatase activities. In vivo, the importance of PTEN catalytic activity in its tumor suppressor functions is underscored by the fact that the majority of PTEN missense mutations detected in tumor specimens target the phosphatase domain and cause a loss in PTEN phosphatase activity.
297 results for "PTEN" in Products
297 results for "PTEN" in Products
PTEN Products
The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10), also known as MMAC1 (mutated in multiple advanced cancers 1), encodes a phosphatase that contains the catalytic signature motif (HCXXGXXRS/T) found in all members of the protein tyrosine phosphatase family. In vitro, the recombinant PTEN has both lipid phosphatase and protein phosphatase activities. In vivo, the importance of PTEN catalytic activity in its tumor suppressor functions is underscored by the fact that the majority of PTEN missense mutations detected in tumor specimens target the phosphatase domain and cause a loss in PTEN phosphatase activity.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, CyTOF-ready, ICFlow, +1 More |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #217702 |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, KO |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #217702R |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Western Blot: PTEN Antibody [NB100-2229]](https://resources.bio-techne.com/images/products/PTEN-Antibody-Western-Blot-NB100-2229-img0001.jpg "Western Blot: PTEN Antibody [NB100-2229]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, ICC |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #217702R |
| Applications: | WB, ICFlow, KO |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #1042824 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL11723 |
| Applications: | IHC, WB |
![Western Blot: PTEN Antibody [NBP3-21201] -](https://resources.bio-techne.com/images/products/nbp3-21201_mouse-pten-mab-cl11723-4520231551470.jpg "Western Blot: PTEN Antibody [NBP3-21201] -")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: PTEN [p Thr366, p Ser370] Antibody [NBP3-12919]](https://resources.bio-techne.com/images/products/PTEN-[p-Thr366--p-Ser370]-Antibody-Western-Blot-NBP3-12919-img0004.jpg "Western Blot: PTEN [p Thr366, p Ser370] Antibody [NBP3-12919]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #217702 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #217702 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL11722 |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: PTEN Antibody [NBP3-21200] -](https://resources.bio-techne.com/images/products/nbp3-21200_mouse-pten-mab-cl11722-452023155031.jpg "Immunohistochemistry-Paraffin: PTEN Antibody [NBP3-21200] -")
| Source: | E. coli |
| Accession #: | P60484 |
| Applications: | InhibAct |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #7O6F4 |
| Applications: | WB, ELISA, ICC/IF, IP, KO |
![Western Blot: PTEN Antibody (7O6F4) [NBP3-15666]](https://resources.bio-techne.com/images/products/PTEN-Antibody-7O6F4-Western-Blot-NBP3-15666-img0005.jpg "Western Blot: PTEN Antibody (7O6F4) [NBP3-15666]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #217702 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #1042838 |
| Applications: | ICC, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, KO |