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Progranulin/PGRN Products
Progranulin, also known as Acrogranin, PCDGF, and Epithelin/Granulin Precursor, is a widely expressed glycoprotein that can undergo proteolysis to generate numerous Granulin peptides. Progranulin plays a role in the regulation of mesothelial differentiation, macrophage development, sexual differentiation of the brain, cartilage proliferation, wound repair, and the development of rheumatoid arthritis and osteoarthritis. It is often upregulated in cancer and contributes to tumor progression. Progranulin upregulation or mutation is associated with several neurological disorders including frontotemporal dementia, Creutzfeldt-Jakob disease, Alzheimer's disease, and motor neuron disease.
24 results for "Progranulin/PGRN" in Products
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Progranulin/PGRN Products
Progranulin, also known as Acrogranin, PCDGF, and Epithelin/Granulin Precursor, is a widely expressed glycoprotein that can undergo proteolysis to generate numerous Granulin peptides. Progranulin plays a role in the regulation of mesothelial differentiation, macrophage development, sexual differentiation of the brain, cartilage proliferation, wound repair, and the development of rheumatoid arthritis and osteoarthritis. It is often upregulated in cancer and contributes to tumor progression. Progranulin upregulation or mutation is associated with several neurological disorders including frontotemporal dementia, Creutzfeldt-Jakob disease, Alzheimer's disease, and motor neuron disease.
24 results for "Progranulin/PGRN" in Products
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Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
| Source : | NS0 |
| Accession # : | P28799 |
| Applications : | Bioactivity |
Not Available in Europe
| Sensitivity : | 0.54 ng/mL |
| Assay Range : | 1.56 - 100 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine, Human Milk) |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Knockout Validated, Western Blot |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #296628 |
| Applications : | Immunoprecipitation, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #296612 |
| Applications : | ELISA |
| Sensitivity : | 0.071 ng/mL |
| Assay Range : | 0.625 - 20 ng/mL (Cell Culture Supernates, Tissue Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #296605 |
| Applications : | Immunohistochemistry, Western Blot |
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #333708 |
| Applications : | ELISA Capture |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #333729 |
| Applications : | ELISA Detection |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Western Blot |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #333708R |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #333731 |
| Applications : | Immunohistochemistry, Western Blot |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #333729R |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | P28798 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #296626 |
| Applications : | ELISA |
