PAFR: Small Molecules and Peptides
PAFR is a seven-transmembrane G protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF binding to PAFR stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system.
2 results for "PAFR Small Molecules and Peptides" in Products
2 results for "PAFR Small Molecules and Peptides" in Products
PAFR: Small Molecules and Peptides
PAFR is a seven-transmembrane G protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF binding to PAFR stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system.
Endogenous platelet-activating factor (PAF)
| Alternate Names: | Platelet-activating factor |
| Chemical Name: | (7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium-4-oxide |
Potent PAF receptor antagonist
| Alternate Names: | Apafant |
| Chemical Name: | 4-[3-[4[(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a]diazepin-2-yl]-1-oxopropyl]morpholine |
| Purity: | ≥98% (HPLC) |
