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Osteoprotegerin/TNFRSF11B: Proteins and Enzymes
Osteoprotegerin (OPG), also known as OCIF and TNFRSF11B, is a secreted TNF superfamily receptor that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts, and endothelial cells. OPG functions as a decoy receptor for TRANCE/RANK L and TRAIL. OPG regulates the cell surface expression of TRANCE and its ability to stimulate osteoclastogenesis. Dysregulation of OPG/TRANCE interactions can lead to juvenile Paget’s disease, osteoporosis, bone loss, and vascular calcification.
3 results for "Osteoprotegerin/TNFRSF11B Proteins and Enzymes" in Products
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Osteoprotegerin/TNFRSF11B: Proteins and Enzymes
Osteoprotegerin (OPG), also known as OCIF and TNFRSF11B, is a secreted TNF superfamily receptor that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts, and endothelial cells. OPG functions as a decoy receptor for TRANCE/RANK L and TRAIL. OPG regulates the cell surface expression of TRANCE and its ability to stimulate osteoclastogenesis. Dysregulation of OPG/TRANCE interactions can lead to juvenile Paget’s disease, osteoporosis, bone loss, and vascular calcification.
3 results for "Osteoprotegerin/TNFRSF11B Proteins and Enzymes" in Products
| Source : | NS0 |
| Accession # : | Q6PI12 |
| Applications : | Bioactivity |
| Source : | CHO |
| Accession # : | AAB53709 |
| Applications : | Bioactivity |
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