Recombinant Human Osteoprotegerin/TNFRSF11B Protein
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | NS0 |
Accession #: | AAB53709.1 |
Structure / Form: | Disulfide-linked homodimer |
Applications: | Bioactivity |
Customers also Viewed
Customers also Purchased
Citations for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (12)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human Osteoprotegerin/TNFRSF11B Protein include:
-
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Diedisheim et al. (2018), Modeling human pancreatic beta cell dedifferentiation Mol Metab, 0(0).
PMID: 29472102 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoE Vorkapic et al. (2018), Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms Mol Med Rep, 0(0).
PMID: 29749489 -
Species: Porcine
Sample Types: Whole Cells
Applications: BioassayCJ Williams et al. (2018), Mutations in osteoprotegerin account for the CCAL1 locus in calcium pyrophosphate deposition disease Osteoarthr. Cartil., 0(0).
PMID: 29578045 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayFeng Z et al. (2013), Osteoprotegerin promotes the proliferation of chondrocytes and affects the expression of ADAMTS-5 and TIMP-4 through MEK/ERK signaling. Mol Med Rep, 8(6):1669-79.
PMID: 24126801 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLane D et al. (2013), Osteoprotegerin (OPG) activates integrin, focal adhesion kinase (FAK), and Akt signaling in ovarian cancer cells to attenuate TRAIL-induced apoptosis. J Ovarian Res, 6(1):82.
PMID: 24267510 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWilson TR et al. (2012), Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 487(7408):505-9.
PMID: 22763448 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: Direct ELISAMabilleau G et al. (2009), Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. PLoS ONE, 4(1):e4173.
PMID: 19137064 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChamoux E et al. (2008), Osteoprotegerin decreases human osteoclast apoptosis by inhibiting the TRAIL pathway. J. Cell. Physiol., 216(2):536-42.
PMID: 18338379 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoTang CH et al. (2007), Attenuation of bone mass and increase of osteoclast formation in decoy receptor 3 transgenic mice. J. Biol. Chem., 282(4):2346-54.
PMID: 17099218 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBogatkevich GS et al. (2007), Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosis. Arthritis Rheum., 56(7):2432-42.
PMID: 17599773 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySecchiero P et al. (2007), Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells. Blood, 111(3):1287-94.
PMID: 18000166 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLocklin RM et al. (2007), Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis. Mol. Cancer Ther., 6(12):3219-28.
PMID: 18065493
There are no citations that match your criteria.
Customer Reviews for Recombinant Human Osteoprotegerin/TNFRSF11B Protein (1)
FAQs for Recombinant Human Osteoprotegerin/TNFRSF11B Protein
-
This protein datasheet indicates I need to use a cross-linking antibody, Catalog # MAB050, for biological activity. What is this antibody and is it really necessary?
The antibody is directed against a 6x histidine repeat and is recommended for use as a cross-linker of proteins with 6x his-tag. Crosslinking is often used for proteins that require receptor trimerization and can result greater biological activity. R&D Systems Quality Control tests the performance of these proteins in the presence of the cross-linking antibody. Therefore, it is necessary to use this antibody when trying to achieve the same level of specific activity described in the datasheet.