Multidrug Transporter Inhibitors: Small Molecules and Peptides
11 results for "Multidrug Transporter Inhibitors Small Molecules and Peptides" in Products
11 results for "Multidrug Transporter Inhibitors Small Molecules and Peptides" in Products
Multidrug Transporter Inhibitors: Small Molecules and Peptides
MRP and OAT3 inhibitor
| Chemical Name: | 4-(Dipropylsulfamoyl)benzoic acid |
| Purity: | ≥98% (HPLC) |
Potent and selective BCRP inhibitor
| Chemical Name: | (3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester |
| Purity: | ≥99% (HPLC) |
Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor
| Chemical Name: | 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine |
| Purity: | ≥99% (HPLC) |
Inhibitor of P-gp-mediated MDR
| Alternate Names: | Valspodar |
| Chemical Name: | 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A |
| Purity: | ≥98% (HPLC) |
High affinity P-gp inhibitor
| Alternate Names: | LY 335979 |
| Chemical Name: | (αR)-4-[(1aα,6α,10bα)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-1-piperazineethanol trihydrochloride |
| Purity: | ≥97% (HPLC) |
P-gp and BCRP inhibitor
| Alternate Names: | GF 120918 |
| Chemical Name: | N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective MRP4 inhibitor
| Chemical Name: | 5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione |
| Purity: | ≥98% (HPLC) |
P-gp inhibitor
| Chemical Name: | 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-2[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective BCRP inhibitor
| Chemical Name: | N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide |
| Purity: | ≥98% (HPLC) |
Potent P-glycoprotein (P-gp) inhibitor
| Chemical Name: | N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent CysLT1 (LTD4) inverse agonist. Also MRP1 inhibitor
| Alternate Names: | L-660711 |
| Chemical Name: | 3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid |
| Purity: | ≥98% (HPLC) |
