MMP-1 Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
22 results for "MMP-1" in Products
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MMP-1 Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
22 results for "MMP-1" in Products
Sensitivity : | 0.095 ng/mL |
Assay Range : | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, Heparin Plasma) |
Applications : | ELISA |
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Applications : | ELISA |
Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors
Assay Range : | 62.5 - 4,000 pg/mL |
Applications : | ELISA |
Contains Mercury, Dispose According to Local, State or Federal Laws.
Sensitivity : | 0.15 pg/mL |
Assay Range : | 0.39 - 25 pg/mL |
Source : | NS0 |
Accession # : | P03956 |
Applications : | Enzyme Activity |
Broad spectrum MMP inhibitor
Chemical Name : | N-[(4'-Bromo[1,1'-biphenyl]-4-yl)sulfonyl]-L-valine |
Purity : | ≥99% (HPLC) |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Capture, Immunohistochemistry, Knockout Validated, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #36665 |
Applications : | Block/Neutralize, Immunohistochemistry, Immunoprecipitation, Knockout Validated, Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #36665R |
Applications : | Immunohistochemistry, Knockout Validated, Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Goat IgG Clone #40013F |
Applications : | Knockout Validated, Western Blot |
Assay Range : | 46.9 - 3,000 pg/mL |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #36607 |
Applications : | Flow Cytometry |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
For use with catalog numbers DMP100, SMP100, PDMP100
Applications : | Control, ELISA |
Applications : | Western Blot |