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Mesothelin: Proteins and Enzymes

Mesothelin, also known as CAK1 and ERC, is derived from a precursor that also includes Megakaryocyte Potentiating Factor (MPF). Following cleavage of the precursor, Mesothelin remains attached to the cell surface via a GPI linkage. Mesothelin is normally expressed on mesothelial cells in the pleura, pericardium, and peritoneum as well as in the developing and postnatal pancreas. It is upregulated in mesotheliomas and a range of carcinomas and adenomas. Mesothelin promotes tumor cell proliferation, migration, anchorage-independent growth, and tumor progression.

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11 results for "Mesothelin Proteins and Enzymes" in Products

Mesothelin: Proteins and Enzymes

Mesothelin, also known as CAK1 and ERC, is derived from a precursor that also includes Megakaryocyte Potentiating Factor (MPF). Following cleavage of the precursor, Mesothelin remains attached to the cell surface via a GPI linkage. Mesothelin is normally expressed on mesothelial cells in the pleura, pericardium, and peritoneum as well as in the developing and postnatal pancreas. It is upregulated in mesotheliomas and a range of carcinomas and adenomas. Mesothelin promotes tumor cell proliferation, migration, anchorage-independent growth, and tumor progression.

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11 results for "Mesothelin Proteins and Enzymes" in Products

C-Terminal

BA

C-Terminal (aa 296-580)

BA, BA

Biotinylated, C-Terminal (aa 296-580)

BA

N-Terminal/MPF

BA

C-Terminal

BA

C-Terminal (aa 296-580)

BA

N-Terminal/MPF

BA

C-terminal

BA

C-terminal

C-Terminal

Catalog #: NBP1-88224PEP
AC
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