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LIGHT/TNFSF14: ELISA Kits

LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.

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4 results for "LIGHT/TNFSF14 ELISA Kits" in Products

4 results for "LIGHT/TNFSF14 ELISA Kits" in Products

LIGHT/TNFSF14: ELISA Kits

LIGHT, also known as TNFSF14, is a homotrimeric glycoprotein in the TNF superfamily. It is expressed on the surface of activated lymphocytes, NK cells, immature dendritic cells, monocytes, and granulocytes. A soluble form can be shed by proteolysis. LIGHT binds and activates HVEM/TNFRSF14 to costimulate Th1 immune responses, enhance CD8+ T cell‑mediated tumor immunity, and regulate allogeneic T cell activation and allograft rejection. In addition, it binds and activates Lymphotoxin beta R/TNFRSF3 to induce apoptosis, cytokine production, mesenteric lymph node organogenesis, and maintenance of lymph node structure and function. It can also bind the soluble human decoy receptor DcR3/TNFRSF6B.

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Sensitivity: 16.5 pg/mL
Applications: ELISA
Assay Range: 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva)
Human LIGHT/TNFSF14 ELISA Calibrator Diluent RD5K Standard Curve
(3)
Assay Range: 62.5 - 4,000 pg/mL
Applications: ELISA
Human LIGHT / TNFSF14 ELISA Standard Curve
Assay Range: 250 - 16,000 pg/mL
Applications: ELISA
Mouse LIGHT / TNFSF14 ELISA Standard Curve

For use with catalog number DLIT00

Applications: ELISA, Ctrl
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