2 results for "Inflammasomes Activators" in Products
Inflammasomes Activators Products
A canonical inflammasome consists of a sensor molecule, which binds to caspase 1 via the adaptor protein ASC (apoptosis-associated speck-like protein). The exact composition of the inflammasome is determined by the type of activator. The most common sensor molecules are NOD-like receptors (NLRs); these include the subtypes NLRP1 (NOD-, LRR- and pyrin domain-containing 1), NLRP3, NLRP6, NLRP7, NLRP12, AND NLRC4 (NOD-, LRR- and CARD-containing 4; IPAF). Other sensor molecules include PYHIN, AIM2 ...
GSDMD (Gasdermin D) agonist, activator of pyroptosis, also GLP-1R agonist
| Chemical Name: | 6,7-Dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-2-quinoxalinamine |
| Purity: | ≥98% (HPLC) |
Potent DPP IV inhibitor; activates NLRP1b inflammasome
| Alternate Names: | Val-boroPro,BXCL 701 |
| Chemical Name: | B-[(2R)-1-[(2S)-2-Amino-3-methyl-1-oxobutyl]-2-pyrrolidinyl]boronic acid methanesulfonate |
| Purity: | ≥98% (HPLC) |
