GLP-1 (7-37)

Name: GLP-1 (7-37)
Brand: Tocris Bioscience
SKU: 5374

Tocris Bioscience a Bio-Techne Brand

Catalog # 5374

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Key Product Details

Description:	Endogenous bioactive GLP-1 receptor ligand
Purity:	≥95% (HPLC)
Molecular Weight:	3355.71

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Biological Activity for GLP-1 (7-37)

GLP-1 (7-37) is a endogenous GLP-1 receptor ligand; bioactive and truncated form of GLP-1; insulinotropic hormone.

Technical Data for GLP-1 (7-37)

M. Wt	3355.71
Formula	C₁₅₁H₂₂₈N₄₀O₄₇
Single Letter Sequence	HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	106612-94-6
PubChem ID	16133830
InChi Key	GCYXWQUSHADNBF-AAEALURTSA-N
Smiles	[H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for GLP-1 (7-37)

Solubility

Soluble to 1mg/ml in water

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References for GLP-1 (7-37)

References are publications that support the biological activity of the product.

Marchetti A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets. Diabetologia 2012 PMID: 22965295
Ban Glucagon-like peptide (GLP)-1(9-36)amide-mediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor. Endocrinology 2010 PMID: 20172966

Citations for GLP-1 (7-37)

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