IL-27: Proteome Profiler Antibody Arrays
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
Products:
2 results for "IL-27 Proteome Profiler Antibody Arrays" in Products
2 results for "IL-27 Proteome Profiler Antibody Arrays" in Products
IL-27: Proteome Profiler Antibody Arrays
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
Products:
