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IL-15: Antibodies

IL-15 (Interleukin 15) is a cytokine that induces or enhances the differentiation, maintenance, or activation of multiple T cell subsets including NK, NKT, Th17, Treg, and CD8+ memory cells. It also induces dendritic cell differentiation and inflammatory activation, exhibits anti-tumor activity, and inhibits the deposition of lipid in adipocytes. Complexes of IL-15 with cell surface IL-15 R alpha interact with complexes of IL-2 R beta and the Common gamma Chain on adjacent cells. This transpresentation mechanism enables cells to respond to IL-15 even if they do not express IL-15 R alpha. Ligation of membrane-associated IL-15/IL-15 R alpha complexes also induces reverse signaling that promotes activation of the IL-15/IL-15 R alpha expressing cells. The activity of circulating IL-15 is limited by its association with soluble IL-15 R alpha.

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168 results for "IL-15 Primary Antibodies" in Products

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IL-15: Antibodies

IL-15 (Interleukin 15) is a cytokine that induces or enhances the differentiation, maintenance, or activation of multiple T cell subsets including NK, NKT, Th17, Treg, and CD8+ memory cells. It also induces dendritic cell differentiation and inflammatory activation, exhibits anti-tumor activity, and inhibits the deposition of lipid in adipocytes. Complexes of IL-15 with cell surface IL-15 R alpha interact with complexes of IL-2 R beta and the Common gamma Chain on adjacent cells. This transpresentation mechanism enables cells to respond to IL-15 even if they do not express IL-15 R alpha. Ligation of membrane-associated IL-15/IL-15 R alpha complexes also induces reverse signaling that promotes activation of the IL-15/IL-15 R alpha expressing cells. The activity of circulating IL-15 is limited by its association with soluble IL-15 R alpha.

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168 results for "IL-15 Primary Antibodies" in Products

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

WB, CyTOF-ready, ICFlow, Neut
WB, IHC, Dual ISH-IHC, Neut
WB, IHC, Neut
IHC, ICC
WB, ICFlow
Catalog #: IC2471S
ICFlow
Catalog #: IC2471V
ICFlow
Catalog #: IC2471G
ICFlow
ICFlow
ICFlow
ELISA

Recombinant Monoclonal Antibody

Catalog #: IC2471T
ICFlow
Catalog #: IC2471R
ICFlow
Catalog #: IC2471U
ICFlow
B/N, WB
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