3 results for "Histamine H4 Receptor Antagonists" in Products
Histamine H4 Receptor Antagonists Products
Histamine H4 receptors are Gαi/o-protein-coupled receptors that were initially cloned in 2000. H4 receptors are expressed at high levels in the gastrointestinal tract, spleen, thymus, medullary cells, bone marrow and peripheral hematopoietic cells, including eosinophils, basophils, mast cells, T lymphocytes, leukocytes and dendritic cells. Moderate expression levels are detected in the brain, heart, liver and lung.
H4 receptors have an important role in inflammation, hematopoiesis and ...
High affinity and selective histamine H4 antagonist; orally bioavailable
| Chemical Name: | 4-[(3R)-3-Amino-1-pyrrolidinyl]-6-(1-methylethyl)-2-pyridinamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective H4 antagonist
| Chemical Name: | 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine |
| Purity: | ≥98% (HPLC) |
Selective H4 antagonist; orally active
| Alternate Names: | VUF 6002 |
| Chemical Name: | 1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate |
| Purity: | ≥98% (HPLC) |
