JNJ 7777120

Tocris Bioscience, part of Bio-Techne | Catalog # 4021

Selective H4 antagonist
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Key Product Details

Description

Selective H4 antagonist

View all Histamine H4 Receptor Antagonists »

Product Description

JNJ 7777120 is a histamine H4 receptor antagonist; displays high affinity (Ki = 4.5 nM) and is >1000-fold selective for H4 over other histamine receptors.

Licensing Information

Sold with the permission of Ortho-McNeil-Janssen Pharmaceuticals, Inc.

Product Specifications

Molecular Weight

277.75

Formula

C14H16ClN3O

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine

CAS Number

459168-41-3

PubChem ID

4908365

InChI Key

HUQJRYMLJBBEDO-UHFFFAOYSA-N

SMILES

ClC1=CC=C(NC(C(N3CCN(C)CC3)=O)=C2)C2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 27.77 100
DMSO 13.89 50

Preparing Stock Solutions for JNJ 7777120

The following data is based on the product molecular weight 277.75

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.60 mL 18.00 mL 36.00 mL
5 mM 0.72 mL 3.60 mL 7.20 mL
10 mM 0.36 mL 1.80 mL 3.60 mL
50 mM 0.07 mL 0.36 mL 0.72 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for JNJ 7777120

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for JNJ 7777120

For research use only

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