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HIF-2 alpha/EPAS1 Products

The hypoxia-inducible transcription factor 2 alpha is stabilized in hypoxic tissue and, similarly to HIF-1 alpha, complexes with aryl hydrocarbon receptor nuclear translocator (ARNT). Both the HIF-1 and HIF-2 complexes bind hypoxia-response elements (HREs) in the promoters of many genes involved in adapting to an environment of insufficient oxygen or hypoxia. HIF-1 and HIF-2 do not appear to be completely redundant, although specific functions are only beginning to be elucidated. Hypoxic tissue environments occur in vascular and pulmonary diseases as well as cancer, indicating the potentially broad impact of gene regulation by both HIF-1 alpha and HIF-2 alpha.

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132 results for "HIF-2 alpha/EPAS1" in Products

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HIF-2 alpha/EPAS1 Products

The hypoxia-inducible transcription factor 2 alpha is stabilized in hypoxic tissue and, similarly to HIF-1 alpha, complexes with aryl hydrocarbon receptor nuclear translocator (ARNT). Both the HIF-1 and HIF-2 complexes bind hypoxia-response elements (HREs) in the promoters of many genes involved in adapting to an environment of insufficient oxygen or hypoxia. HIF-1 and HIF-2 do not appear to be completely redundant, although specific functions are only beginning to be elucidated. Hypoxic tissue environments occur in vascular and pulmonary diseases as well as cancer, indicating the potentially broad impact of gene regulation by both HIF-1 alpha and HIF-2 alpha.

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132 results for "HIF-2 alpha/EPAS1" in Products

ChIP, Dual ISH-IHC, ELISA, Flow, Func, GS, ICC/IF, IHC, IP, KD, KO, PAGE, Simple Western, WB
ChIP, ELISA, Flow, Func, GS, ICC/IF, IHC, IP, KD, Simple Western, WB
ChIP, ELISA, Flow, ICC/IF, IHC, IP, KD, Simple Western, WB

Recombinant Monoclonal Antibody.

IHC

Recombinant Monoclonal Antibody.

WB, ICC

Recombinant Monoclonal Antibody.

AP, ELISA, MA, WB
AP, ELISA, MA, PAGE, WB

Recombinant Monoclonal Antibody

Catalog #: NB100-122PEP
AC
Catalog #: NBP2-58653PEP
AC
Catalog #: NBP2-76564PEP
AC
ICC/IF
ICC/IF
ELISA, ICC/IF

Recombinant monoclonal antibody expressed in HEK293F cells

Contains 4 membranes - each spotted in duplicate with 26 different cell stress antibodies

High affinity and selective HIF-2α inhibitor

ChIP, Dual ISH-IHC, ELISA, Flow, Func, GS, ICC/IF, IHC, IP, KD, KO, PAGE, Simple Western, WB
ChIP, Dual ISH-IHC, ELISA, Flow, Func, GS, ICC/IF, IHC, IP, KD, KO, PAGE, Simple Western, WB
ChIP, ELISA, Flow, Func, GS, ICC/IF, IHC, IP, KD, Simple Western, WB
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