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5 results for "HDAC10 Small Molecules and Peptides" in Products

HDAC10: Small Molecules and Peptides

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by ...

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Histone deacetylase inhibitor

Alternate Names: VPA,Sodium Valproate
Chemical Name: Sodium 2-propylpentanoate
Histone deacetylase inhibitor

Potent histone deacetylase inhibitor

Chemical Name: (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Purity: ≥95% (HPLC)
Potent histone deacetylase inhibitor

Class I and II HDAC inhibitor

Alternate Names: Vorinostat
Chemical Name: N-Hydroxy-N'-phenyloctanediamide
Purity: ≥98% (HPLC)
Class I and II HDAC inhibitor

Histone deacetylase inhibitor

Alternate Names: 4-PB,Sodium phenylbutyrate
Chemical Name: 4-Phenylbutyric acid, sodium salt
Purity: ≥98% (HPLC)
Histone deacetylase inhibitor

Potent class I and IIb HDAC inhibitor

Chemical Name: 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide
Purity: ≥98% (HPLC)
Potent class I and IIb HDAC inhibitor
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