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5 results for "Glycine Receptor Agonists" in Products

Glycine Receptor Agonists Products

Glycine receptors (GlyR) are members of the cys-loop family of ligand-gated ion channels, responsible for mediating the inhibitory effects of glycine. They are widely distributed throughout the CNS, particularly within the hippocampus, spinal cord and brain stem.

Glycine receptors exist as pentameric proteins, homo-oligomers of the α isoforms (α1, α2, α3 or α4) or hetero-oligomers which also contain the β-subtype variant (β1) which is essential for targeting ...

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Non-selective endogenous glycine receptor agonist

Endogenous potentiator of NMDA receptors

PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist

PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist

Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant

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