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312 results for "Fas Ligand/TNFSF6" in Products

Fas Ligand/TNFSF6 Products

Fas Ligand (FasL), also known as CD178, CD95L, or TNFSF6, is a transmembrane protein homotrimer that binds to Fas/CD95 and triggers apoptosis in the Fas-expressing cell. Fas Ligand also binds the soluble decoy receptor DcR3. It is expressed on activated Th1 cells, CD8+ cytotoxic T cells, and NK cells. A soluble form can be released which remains trimeric and retains the ability to bind Fas. Fas Ligand-induced apoptosis plays a central role in the development of immune tolerance and the maintance of immune privileged sites. Tumor cells can evade immune surveillance by upregulating Fas Ligand to kill tumor infiltrating lymphocytes. In gld mice, a Fas Ligand point mutation is the cause of severe lymphoproliferation and systemic autoimmunity.

Control for use with Human and Non-Human Primate Fas Ligand/TNFSF6 Simple Plex Cartridge Kit

Applications: Ctrl, Simple Plex
Sensitivity: 5.1 pg/mL
Applications: ELISA
Assay Range: 15.6 - 1,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma)
Human Fas Ligand/TNFSF6 Standard Curve
(4)
Source: CHO
Accession #: Q53ZZ1
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Sensitivity: 3.9 pg/mL
Applications: ELISA
Assay Range: 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma)
Mouse Fas Ligand/TNFSF6 ELISA Standard Curve
(2)
Assay Range: 31.2 - 2,000 pg/mL
Applications: ELISA
Human Fas Ligand / TNFSF6 ELISA Standard Curve
Source: CHO
Accession #: P41047
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Mouse
Details: Rat IgM Monoclonal Clone #A11
Applications: IHC, ICC/IF, Flow
Immunohistochemistry-Paraffin: Fas Ligand/TNFSF6 Antibody (A11) [NBP1-97519]
Assay Range: 15.6 - 1,000 pg/mL
Applications: ELISA
Mouse Fas Ligand / TNFSF6 ELISA Standard Curve

Clone NOK-1 was used by HLDA to establish CD designation.

Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #NOK-1
Applications: WB, ICC/IF, Flow, IP
Flow Cytometry: Fas Ligand/TNFSF6 Antibody (NOK-1) - BSA Free [NBP3-09151]
(2)
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #14C2
Applications: ELISA, Flow, IP, WB (-)
Flow Cytometry: Fas Ligand/TNFSF6 Antibody (14C2) - BSA Free [NB100-63072]
(3)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC
Immunohistochemistry-Paraffin: Fas Ligand/TNFSF6 Antibody [NBP2-49160]
(4)
Source: NS0
Accession #: Q544E9
Applications: BA, BA
R&D Systems Recombinant Proteins and Enzymes
Applications: WB
Western Blot: Fas Ligand/TNFSF6 Overexpression Lysate [NBL1-10600]
Applications: AC
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