2 results for "Epithelial Sodium Channels (ENaC) Blockers" in Products
Epithelial Sodium Channels (ENaC) Blockers Products
Epithelial sodium channels (ENaCs) are members of the ENaC/Deg (epithelial amiloride-sensitive Na+ channel and degenerin) family of ion channels. They are highly selective Na+ channels that are localized to polarized epithelial cells. ENaCs are responsible for sodium reabsorption in the distal kidney tubule, and have similar functions in the alveoli and the colon. These channels transport Na+ across the epithelium using energy from Na+, K+-ATPase, and constitute one of the essential mechanisms ...
Inhibits TRPP3-mediated currents; also inhibits epithelial Na+ channels
| Chemical Name: | 3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt |
| Purity: | ≥98% (HPLC) |
NCX inhibitor, Deg/ENaC channel blocker; amiloride (Cat. No. 0890) derivative
| Chemical Name: | N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
