Endothelin-1: ELISA Kits
Endothelin-1 (ET-1) is a vascular endothelium derived peptide that acts as a potent vasoconstrictor. It is processed by a furin-like protease to yield a peptide termed Big ET-1. Big ET-1 is then cleaved by ECE-1, producing the mature form ET-1 (1-21). ET-1 expression is induced by mechanical stimulation, various hormones, and pro-inflammatory cytokines. Its production is inhibited by nitric oxide, prostacyclin, and atrial natriuretic peptide (ANP). ET-1 exerts its vasoconstrictor effects primarily through the receptor ETA on vascular smooth muscle cells. It also acts through the ETB receptor on vascular smooth muscle and endothelial cells. ET-1 additionally stimulates cardiac myocyte proliferation and contractility, regulates secretion by hypothalamic and pituitary cells, and promotes neutrophil extravasation and activation.
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Endothelin-1: ELISA Kits
Endothelin-1 (ET-1) is a vascular endothelium derived peptide that acts as a potent vasoconstrictor. It is processed by a furin-like protease to yield a peptide termed Big ET-1. Big ET-1 is then cleaved by ECE-1, producing the mature form ET-1 (1-21). ET-1 expression is induced by mechanical stimulation, various hormones, and pro-inflammatory cytokines. Its production is inhibited by nitric oxide, prostacyclin, and atrial natriuretic peptide (ANP). ET-1 exerts its vasoconstrictor effects primarily through the receptor ETA on vascular smooth muscle cells. It also acts through the ETB receptor on vascular smooth muscle and endothelial cells. ET-1 additionally stimulates cardiac myocyte proliferation and contractility, regulates secretion by hypothalamic and pituitary cells, and promotes neutrophil extravasation and activation.
5 results for "Endothelin-1 ELISA Kits" in Products
Sensitivity : | 0.207 pg/mL |
Assay Range : | 0.39 - 25 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
Applications : | ELISA |
Sensitivity : | 0.102 pg/mL |
Assay Range : | 0.34 - 250 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Urine) |
Applications : | ELISA |
Assay Range : | 3.91 - 250 pg/mL |
Applications : | ELISA |