ECE-2 Products
ECE-2 is a zinc protease of the neprilysin (NEP) family, which also includes ECE-1, PEX, XCE, DINE, Kell and several NEPlike proteins. ECE-2 is a type II transmembrane protein with a short cytoplasmic tail and a large ectodomain. Three alternatively spliced forms differ in their cytoplasmic tail. In addition to big endothelin-1, ECE-2 cleaves a variety of bioactive peptides such as bradykinin, neurotensin, angiotensin I, substance P, dynorphin B, proenkephalin-derived peptides such as peptide E, BAM22 and BAM18, and PENLEN, an endogenous inhibitor of prohormone convertase 1. Together with ECE-1, it is also involved in degradation of beta-amyloid peptide.
70 results for "ECE-2" in Products
70 results for "ECE-2" in Products
ECE-2 Products
ECE-2 is a zinc protease of the neprilysin (NEP) family, which also includes ECE-1, PEX, XCE, DINE, Kell and several NEPlike proteins. ECE-2 is a type II transmembrane protein with a short cytoplasmic tail and a large ectodomain. Three alternatively spliced forms differ in their cytoplasmic tail. In addition to big endothelin-1, ECE-2 cleaves a variety of bioactive peptides such as bradykinin, neurotensin, angiotensin I, substance P, dynorphin B, proenkephalin-derived peptides such as peptide E, BAM22 and BAM18, and PENLEN, an endogenous inhibitor of prohormone convertase 1. Together with ECE-1, it is also involved in degradation of beta-amyloid peptide.
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #233914 |
| Applications: | WB, IHC |
| Source: | NS0 |
| Accession #: | EAW78275 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #233914 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #233914 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #233914 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #233914 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #233914 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #233914 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #233914 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #233914 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry: ECE-2 Antibody [NBP1-81495]](https://resources.bio-techne.com/images/products/ECE-2-Antibody-Immunohistochemistry-NBP1-81495-img0008.jpg "Immunohistochemistry: ECE-2 Antibody [NBP1-81495]")
Neutral endopeptidase and endothelin converting enzyme inhibitor
| Chemical Name: | N-[N-[[(6-Deoxy-α-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl]-L-tryptophan disodium salt |
| Purity: | ≥95% (HPLC) |
| Reactivity: | Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: ECE-2 Antibody [NBP1-69061]](https://resources.bio-techne.com/images/products/ECE2-Antibody-Western-Blot-NBP1-69061-img0002.jpg "Western Blot: ECE-2 Antibody [NBP1-69061]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: ECE-2 Antibody [NBP2-56945]](https://resources.bio-techne.com/images/products/ECE-2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-56945-img0001.jpg "Immunocytochemistry/ Immunofluorescence: ECE-2 Antibody [NBP2-56945]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: ECE-2 AntibodyBSA Free [NBP3-05677]](https://resources.bio-techne.com/images/products/ECE-2 "Western Blot: ECE-2 AntibodyBSA Free [NBP3-05677]")