Dopamine D5R/DRD5: Small Molecules and Peptides
DRD5 is the D5 subtype of the dopamine receptor, a G protein-coupled receptor which stimulates adenylyl cyclase. DRD5 is expressed in neurons in the limbic regions of the brain and has a 10-fold higher affinity for dopamine than the D1 subtype. DRD5 shows a trafficking profile distinct from that of any of the other dopamine receptors. Endocytosis of DRD5 can be achieved both homologously, through direct receptor activation by an agonist, and also heterologously, due to independent activation of protein kinase C (PKC).
Products:
6 results for "Dopamine D5R/DRD5 Small Molecules and Peptides" in Products
6 results for "Dopamine D5R/DRD5 Small Molecules and Peptides" in Products
Dopamine D5R/DRD5: Small Molecules and Peptides
DRD5 is the D5 subtype of the dopamine receptor, a G protein-coupled receptor which stimulates adenylyl cyclase. DRD5 is expressed in neurons in the limbic regions of the brain and has a 10-fold higher affinity for dopamine than the D1 subtype. DRD5 shows a trafficking profile distinct from that of any of the other dopamine receptors. Endocytosis of DRD5 can be achieved both homologously, through direct receptor activation by an agonist, and also heterologously, due to independent activation of protein kinase C (PKC).
Products:
Endogenous agonist at dopamine D1-5 receptors
| Chemical Name: | 3,4-Dihydroxyphenethylamine hydrochloride |
| Purity: | ≥99% (HPLC) |
Selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker
| Alternate Names: | (R)-(+)-SCH 23390 hydrochloride |
| Chemical Name: | (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride |
| Purity: | ≥98% (HPLC) |
Caged dopamine; photolysed by UV light
| Purity: | ≥98% (HPLC) |
Dopamine precursor
| Alternate Names: | Levodopa |
| Chemical Name: | L-3,4-Dihydroxyphenylalanine |
| Purity: | ≥98% (HPLC) |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
High affinity D1-like antagonist
| Alternate Names: | Ecopipam hydrobromide |
| Chemical Name: | (6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide |
| Purity: | ≥98% (HPLC) |
