CXCL17/VCC-1: Proteins and Enzymes

Dendritic cell and monocyte chemokine-like protein (DMC), also known as VEGF-correlated chemokine-1 (VCC-1) and CXCL17, is a novel secreted molecule that belongs to the intercrine alpha (or CXC) family of chemokines. It has no predicted N-glycosylation sites, so cleavage of a 22 amino acid (aa) signal sequence likely results in a mature human DMC of 97 aa and 11 kDa. CXCL17 is constitutively produced by bronchiolar, mammary, and intestinal epithelium, vascular endothelial cells, and multiple ...