COMP/Thrombospondin-5 Products
COMP (Cartilage Oligomeric Matrix Protein), also known as Thrombospondin-5, is a multidomain calcium binding protein that associates with other extracellular matrix molecules. COMP associates into disulfide-linked homopentamers with a central hub and peripheral globular domains connected by flexible strands.
An axial pore is formed by the coiled coil assembly and binds vitamin D3 which is involved in bone and cartilage metabolism. An RGD sequence in the third TSP type-3 repeat mediates chondrocyte attachment via Integrins a5b1 or aVb3. COMP is upregulated in rheumatoid arthritis and osteoarthritis, hepatocellular carcinomas, chronic pancreatitis, and pancreatic carcinomas. Several mutations in COMP are associated with skeletal dysplasias.
Products:
117 results for "COMP/Thrombospondin-5" in Products
117 results for "COMP/Thrombospondin-5" in Products
COMP/Thrombospondin-5 Products
COMP (Cartilage Oligomeric Matrix Protein), also known as Thrombospondin-5, is a multidomain calcium binding protein that associates with other extracellular matrix molecules. COMP associates into disulfide-linked homopentamers with a central hub and peripheral globular domains connected by flexible strands.
An axial pore is formed by the coiled coil assembly and binds vitamin D3 which is involved in bone and cartilage metabolism. An RGD sequence in the third TSP type-3 repeat mediates chondrocyte attachment via Integrins a5b1 or aVb3. COMP is upregulated in rheumatoid arthritis and osteoarthritis, hepatocellular carcinomas, chronic pancreatitis, and pancreatic carcinomas. Several mutations in COMP are associated with skeletal dysplasias.
Products:
| Sensitivity: | 0.036 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.156 - 10 ng/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma) |
Simple Plex Human COMP/Thrombospondin-5 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Source: | NS0 |
| Accession #: | P49747 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #2127-F5 |
| Applications: | WB, IP |
| Applications: | ELISA |
Control for use with Human COMP/Thrombospondin-5 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Assay Range: | 39.1 - 2,500 pg/mL |
| Applications: | ELISA |
For use with catalog number DCMP0
| Applications: | Ctrl |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #360215 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: COMP/Thrombospondin-5 AntibodyBSA Free [NBP2-92733]](https://resources.bio-techne.com/images/products/COMP-Thrombospondin-5-Antibody-Western-Blot-NBP2-92733-img0003.jpg "Western Blot: COMP/Thrombospondin-5 AntibodyBSA Free [NBP2-92733]")
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: COMP/Thrombospondin-5 Antibody [NBP2-99528]](https://resources.bio-techne.com/images/products/COMP-Thrombospondin-5-Antibody-Western-Blot-NBP2-99528-img0002.jpg "Western Blot: COMP/Thrombospondin-5 Antibody [NBP2-99528]")
| Source: | NS0 |
| Accession #: | Q9R0G6 |
| Applications: | BA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C1 |
| Applications: | IHC, WB |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Applications: | ELISA |
| Applications: | ELISA |
| Applications: | WB |
![Western Blot: COMP/Thrombospondin-5 Overexpression Lysate [NBP2-09056]](https://resources.bio-techne.com/images/products/COMP-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09056-img0001.jpg "Western Blot: COMP/Thrombospondin-5 Overexpression Lysate [NBP2-09056]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #360215 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #360215 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #360215 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |