CCL4/MIP-1 beta: Proteins and Enzymes
CCL4/MIP-1 beta is a beta chemokine that is secreted at sites of inflammation by activated leukocytes, lymphocytes, vascular endothelial cells, and pulmonary smooth muscle cells. It attracts a variety of immune cells to sites of microbial infection as well as to other pathologic inflammation such as allergic asthma and ischemic myocardium. CCL4 is secreted from activated monocytes as a heterodimer with CCL3/MIP-1 alpha. It signals through CCR5, and an N-terminally trimmed form additionally interacts with CCR1 and CCR2. In humans, the ability of CCL4 to bind CCR5 inhibits the cellular entry of M-tropic HIV-1 which utilizes CCR5 as a coreceptor.
7 results for "CCL4/MIP-1 beta Proteins and Enzymes" in Products
7 results for "CCL4/MIP-1 beta Proteins and Enzymes" in Products
CCL4/MIP-1 beta: Proteins and Enzymes
CCL4/MIP-1 beta is a beta chemokine that is secreted at sites of inflammation by activated leukocytes, lymphocytes, vascular endothelial cells, and pulmonary smooth muscle cells. It attracts a variety of immune cells to sites of microbial infection as well as to other pathologic inflammation such as allergic asthma and ischemic myocardium. CCL4 is secreted from activated monocytes as a heterodimer with CCL3/MIP-1 alpha. It signals through CCR5, and an N-terminally trimmed form additionally interacts with CCR1 and CCR2. In humans, the ability of CCL4 to bind CCR5 inhibits the cellular entry of M-tropic HIV-1 which utilizes CCR5 as a coreceptor.
| Source: | E. coli |
| Accession #: | P13236.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q5QNV9 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P50230 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P13236 |
| Applications: | Bind |
| Source: | E. coli |
| Accession #: | NP_001005250 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | AAL16933 |
| Applications: | BA |
| Applications: | PAGE, Bioactivity |