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19 results for "CCL2/JE/MCP-1" in Products
CCL2/JE/MCP-1 Products
CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.
Reactivity:
Human
Assay Range:
31.2-2000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine)
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
7.81-500 pg/mL (Cell Culture Supernates, Tissue Lysates, Tissue Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Applications:
ELISA
Reactivity:
Canine
Assay Range:
15.6-1000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Applications:
ELISA
Reactivity:
Human
Assay Range:
2.813-180 pg/ml (example only; lot dependent)
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
7-450 pg/ml (example only; lot dependent)
Applications:
ELISA
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #23007
Applications:
IHC, WB, ELISA, ELISA(Cap), ELISA(Det), + 2 More
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA, ELISA(Cap), ELISA(Det), B/N
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA, ELISA(Cap), ELISA(Det), B/N
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N
Reactivity:
Canine
Details:
Goat IgG Polyclonal
Applications:
WB, B/N, ICC/IF
Reactivity:
Cotton Rat
Details:
Mouse IgG1 Monoclonal Clone #238607
Applications:
WB
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #23002
Applications:
IHC
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #24822
Applications:
WB, B/N
Reactivity:
Canine
Details:
Mouse IgG2B Monoclonal Clone #280707
Applications:
WB
Reactivity:
Mouse
Details:
Rat IgG2B Monoclonal Clone #123616
Applications:
B/N
Reactivity:
Mouse
Details:
Rat IgG2B Monoclonal Clone #123616R
Applications:
Flow
Reactivity:
Human, Mouse
Details:
Rabbit IgG Kappa Monoclonal Clone #11k2
Applications:
ELISA, B/N
Reactivity:
Mouse
Details:
Rabbit IgG Monoclonal Clone #001
Applications:
ELISA
Reactivity:
Mouse
Details:
Rabbit IgG Monoclonal Clone #017
Applications:
ELISA