CCK-AR: Small Molecules and Peptides
The physiologic actions of the cholecystokinin (CCK) family of peptide hormones are mediated through two classes of G protein-coupled receptors GPCR), CCK-AR and CCK-BR. CCK-AR is a 428 amino acid protein with 7 putative transmembrane domains. This GPCR is involved in gall bladder contraction, insulin secretion, and has also been described in specific regions of the central nervous system. CCK-AR has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction.
Products:
4 results for "CCK-AR Small Molecules and Peptides" in Products
4 results for "CCK-AR Small Molecules and Peptides" in Products
CCK-AR: Small Molecules and Peptides
The physiologic actions of the cholecystokinin (CCK) family of peptide hormones are mediated through two classes of G protein-coupled receptors GPCR), CCK-AR and CCK-BR. CCK-AR is a 428 amino acid protein with 7 putative transmembrane domains. This GPCR is involved in gall bladder contraction, insulin secretion, and has also been described in specific regions of the central nervous system. CCK-AR has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction.
Products:
Selective, orally active CCK1 receptor antagonist
| Alternate Names: | L-364,718,MK 329 |
| Chemical Name: | N-[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide |
| Purity: | ≥98% (HPLC) |
CCK agonist
| Purity: | ≥95% (HPLC) |
Potent and selective CCK1 antagonist
| Alternate Names: | Lintitript |
| Chemical Name: | 2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid |
| Purity: | ≥98% (HPLC) |
Potent and selective CCK1 agonist; suppresses feeding
| Purity: | ≥95% (HPLC) |
