A-71623
Tocris Bioscience, part of Bio-Techne | Catalog # 2411
Potent and selective CCK1 agonist; suppresses feeding
Key Product Details
Description
Potent and selective CCK1 agonist; suppresses feeding
Product Description
A-71623 is a potent CCK1 agonist (IC50 = 3.7 nM) with 1200-fold selectivity over the CCK2 receptor. Suppresses food intake following central or peripheral administration.Product Specifications
Molecular Weight
840.97
Formula
C44H56N8O9
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
130408-77-4
PubChem ID
121964
InChI Key
KNHCBYMGWWTGSO-ZYADHFCISA-N
SMILES
O=C(N[C@H]([C@](N[C@@H](CC(O)=O)C(N(C)[C@@H](CC3=CC=CC=C3)C(N)=O)=O)=O)CCCCNC(NC4=CC=CC=C4C)=O)[C@@H](NC(OC(C)(C)C)=O)CC1=CNC2=C1C=CC=C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in 20mM PBS buffer |
Calculators
Molarity Calculator
Dilution Calculator
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Background References
References are publications that support the biological activity of the product.
- DeNinno Development of CCK-tetrapeptide analogues as potent and selective CCK-A receptor agonists. J.Med.Chem.
- Lin Characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, A-71623 and A-70874, that exhibit high potency and selectivity for cholecystokinin-A receptors. Mol.Pharmacol.
- Asin A-71623, a selective CCK-A receptor agonist, suppresses food intake in the mouse, dog, and monkey. Pharmacol.Biochem.Behav. 1992 PMID: 1513850
Product Specific Notices for A-71623
For research use only
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