Caspase-7 Products
Caspase-7, also known as CMH-1, ICE-LAP3, and Mch3, is a 32 kDa member of the peptidase C14A/IL-1 beta-converting family of enzymes. It is widely expressed, except in the brain and is best known as an executioner caspase of the apoptotic cascade. Caspase-7 cleaves multiple substrates, including PARP, Pro-Caspase-6, Gas2, and Calpstatin.
Pro-Caspase-7 undergoes proteolytic cleavage to generate a propeptide, a p20, and a p12 subunit. The p20 and p12 subunits noncovalently heterodimerize, and subsequently associate with another p20-p12 heterodimer to form an active antiparallel homodimer. p20 may be additionally processed to generate p18, while p12 may be additionally processed to generate p11. Caspase-7 can be cleaved by multiple proteases including Caspases-1, -3, -8, and -10, Granzyme B, Calpain-1, and Caspase-7 itself. Caspase-7 is found in both the cytosol and nucleus.
Products:
153 results for "Caspase-7" in Products
153 results for "Caspase-7" in Products
Caspase-7 Products
Caspase-7, also known as CMH-1, ICE-LAP3, and Mch3, is a 32 kDa member of the peptidase C14A/IL-1 beta-converting family of enzymes. It is widely expressed, except in the brain and is best known as an executioner caspase of the apoptotic cascade. Caspase-7 cleaves multiple substrates, including PARP, Pro-Caspase-6, Gas2, and Calpstatin.
Pro-Caspase-7 undergoes proteolytic cleavage to generate a propeptide, a p20, and a p12 subunit. The p20 and p12 subunits noncovalently heterodimerize, and subsequently associate with another p20-p12 heterodimer to form an active antiparallel homodimer. p20 may be additionally processed to generate p18, while p12 may be additionally processed to generate p11. Caspase-7 can be cleaved by multiple proteases including Caspases-1, -3, -8, and -10, Granzyme B, Calpain-1, and Caspase-7 itself. Caspase-7 is found in both the cytosol and nucleus.
Products:
| Source: | E. coli |
| Accession #: | P55210 |
| Applications: | EnzAct |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #MCH3101.62 |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #25B881.1 |
| Applications: | IHC, WB |
![Western Blot: Caspase-7 Antibody (25B881.1)BSA Free [NB100-56529]](https://resources.bio-techne.com/images/products/Caspase-7-Antibody-25B881-1-Western-Blot-NB100-56529-img0008.jpg "Western Blot: Caspase-7 Antibody (25B881.1)BSA Free [NB100-56529]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #Mch3 1-1-11 |
| Applications: | WB, Mycoplasma, Simple Western |
![Knockdown Validated: Caspase-7 Antibody (Mch3 1-1-11) [NB500-206]](https://resources.bio-techne.com/images/products/Caspase-7-Antibody-Mch3-1-1-11-Knockdown-Validated-NB500-206-img0004.jpg "Western Blot: Caspase-7 Antibody (Mch3 1-1-11) [NB500-206]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #25B881.1 |
| Applications: | IHC, WB |
![Western Blot: Caspase-7 Antibody (25B881.1)Azide and BSA Free [NBP2-80615]](https://resources.bio-techne.com/images/products/Caspase-7-Antibody-25B881-1-Azide-and-BSA-Free-Western-Blot-NBP2-80615-img0002.jpg "Western Blot: Caspase-7 Antibody (25B881.1)Azide and BSA Free [NBP2-80615]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #MCH3101.62 |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #MCH3101.62 |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #10-1-62 |
| Applications: | IHC, WB |
![Western Blot: Caspase-7 Antibody (10-1-62) [NBP1-19230]](https://resources.bio-techne.com/images/products/Caspase-7-Antibody-10-1-62-Western-Blot-NBP1-19230-img0004.jpg "Western Blot: Caspase-7 Antibody (10-1-62) [NBP1-19230]")
| Reactivity: | Human, Mouse, Rat, Canine, Primate, +4 More |
| Details: | Mouse IgG2B Monoclonal Clone #7-1-11 |
| Applications: | IHC, WB |
![Western Blot: Caspase-7 Antibody (7-1-11) [NBP1-19229]](https://resources.bio-techne.com/images/products/Caspase-7-Antibody-7-1-11-Western-Blot-NBP1-19229-img0008.jpg "Western Blot: Caspase-7 Antibody (7-1-11) [NBP1-19229]")
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #MCH3101.62 |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #MCH3101.62 |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #MCH3101.62 |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #MCH3101.62 |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #MCH3101.62 |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #MCH3101.62 |
| Applications: | WB, KO |