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beta-Catenin Products
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
32 results for "beta-Catenin" in Products
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beta-Catenin Products
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
32 results for "beta-Catenin" in Products
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
Wnt/β-catenin signaling inhibitor; axin stabilizer
| Chemical Name : | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity : | ≥98% (HPLC) |
Potent tankyrase inhibitor
| Alternate Names : | XAV939 Wnt Signaling Inhibitor |
| Chemical Name : | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity : | ≥98% (HPLC) |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Chromatin Immunoprecipitation, CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG3 Clone #196618 |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
XAV 939 synthesized to cGMP guidelines
| Chemical Name : | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity : | ≥99% |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #196624 |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Assay Range : | 312 - 20,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #196621 |
| Applications : | Immunohistochemistry, Western Blot |
Wnt signaling inhibitor; inhibits β-catenin-transcription factor interactions
| Purity : | ≥95% (HPLC) |
Wnt pathway inhibitor; induces degradation of active β-catenin
| Chemical Name : | Trispiro[3H-indole-3,2'-[1,3]dioxane-2'',3'''-[3H]indole]-2,2'''(1H,1'''H)-dione |
| Purity : | ≥97% (HPLC) |
Frizzled 4 allosteric agonist; exhibits biased signaling; preserves stemness
| Chemical Name : | 3-Hydroxy-5-[[(2-Naphthalenylamino)carbonyl]amino]benzoic acid |
| Purity : | ≥98% (HPLC) |
Potent inhibitor of Wnt/β-catenin signaling
| Chemical Name : | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #196624 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #196624 |
| Applications : | Flow Cytometry |
Inhibits TCF/β-catenin-mediated transcription
| Chemical Name : | (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide |
| Purity : | ≥98% (HPLC) |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #196624 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #196624 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #196624 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #196624 |
| Applications : | Flow Cytometry |
Inhibitor of Wnt/β-catenin signaling
| Chemical Name : | N-[4-(4-Ethyl-1-piperazinyl)phenyl]-2-oxo-2H-1-benzopyran-3-carboxamide |
| Purity : | ≥98% (HPLC) |
Inhibits β-catenin-responsive transcription (CRT)
| Chemical Name : | 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedion |
| Purity : | ≥99% (HPLC) |
Inhibitor of Wnt/β-catenin signaling
| Chemical Name : | 2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide |
| Purity : | ≥99% (HPLC) |
