796 results for "beta-Catenin" in Products
beta-Catenin Products
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
Potent tankyrase inhibitor
| Alternate Names: | XAV939 Wnt Signaling Inhibitor |
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ChIP, CyTOF-ready, +2 More |
| Reactivity: | Human, Mouse, Rat, Primate, Chicken, +3 More |
| Details: | Mouse IgG1 Monoclonal Clone #12F7 |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +1 More |
Potent inhibitor of Wnt/β-catenin signaling
| Chemical Name: | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat, Canine, Zebrafish, +2 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +2 More |
Wnt/β-catenin signaling inhibitor; axin stabilizer
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% (HPLC) |
Selective peptide-based β-catenin Degrader (PROTAC®)
| Purity: | ≥95% (HPLC) |
| Reactivity: | Human, Mouse, Rat, Primate, Chicken, +1 More |
| Details: | Mouse IgG1 Monoclonal Clone #12F7 |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +2 More |
| Reactivity: | Human |
| Details: | Mouse IgG3 Monoclonal Clone #196618 |
| Applications: | WB, IHC, ICC |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #6A3P2 |
| Applications: | IHC, WB, ELISA, ICC/IF, IP, +2 More |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #196624 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTNNB1/2030R |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready, +1 More |
| Assay Range: | 312 - 20,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #196621 |
| Applications: | WB, IHC, mIF |
XAV 939 synthesized to cGMP guidelines
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥99% |
| Reactivity: | Human, Mouse, Rat, Monkey, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #OTI12H7 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat, Fish |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL3689 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ChIP, CyTOF-ready, ICC, +1 More |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Monoclonal Clone #196624 |
| Applications: | WB, CyTOF-ready, ICFlow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ChIP, CyTOF-ready, ICC, +1 More |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ChIP, CyTOF-ready, ICC, +1 More |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ChIP, CyTOF-ready, ICC, +1 More |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ChIP, CyTOF-ready, ICC, +1 More |