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Bcl-w Products
Bcl-w is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. Bcl-w is an anti-apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Bcl-w is required for normal sperm maturation. Natural Bcl-w contains a carboxyl-terminal mitochondria targeting sequence.
9 results for "Bcl-w" in Products
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Bcl-w Products
Bcl-w is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. Bcl-w is an anti-apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Bcl-w is required for normal sperm maturation. Natural Bcl-w contains a carboxyl-terminal mitochondria targeting sequence.
9 results for "Bcl-w" in Products
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines
| Chemical Name : | 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide |
| Purity : | ≥98% (HPLC) |
Inhibitor of Bcl-2 family members; antiapoptotic
| Alternate Names : | GX15-070 |
| Chemical Name : | 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate |
| Purity : | ≥98% (HPLC) |
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
| Chemical Name : | 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide |
| Purity : | ≥98% (HPLC) |
| Source : | E. coli |
| Accession # : | Q92843 |
| Applications : | Inhibition Activity |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #90336 |
| Applications : | Block/Neutralize |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #90316 |
| Applications : | Western Blot |
| Applications : | Western Blot |
