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3 results for "Bax Small Molecules and Peptides" in Products

Bax Small Molecules and Peptides

B cell leukemia/lymphoma-2 associated X protein (Bax) is a pro-apoptotic member of the Bcl-2 family of proteins found in many cell types. Bax is a cytosolic protein that translocates to the mitochondria and participates in Cytochrome c release in response to apoptotic stimuli. Aberrant expression of Bcl-2 family members can inappropriately promote or prevent apoptosis. Increased expression of Bax is associated with the apoptotic loss of neurons in Parkinson's disease.

Allosteric inhibitor of Bax channel activation

Alternate Names:
BAI1
Chemical Name:
3,6-Dibromo-α-(1-piperazinylmethyl)-9H-carbazole-9-ethanol dihydrochloride
Purity:
≥98%
Allosteric inhibitor of Bax channel activation

High affinity and selective activator of Bax

Chemical Name:
2-[(2-Nitro-9H-fluorene-9-ylidene)methyl]phenol
Purity:
≥98%
High affinity and selective activator of Bax

Allosteric inhibitor of Bax channel activation

Alternate Names:
BAI1
Chemical Name:
3,6-Dibromo-α-(1-piperazinylmethyl)-9H-carbazole-9-ethanol dihydrochloride
Purity:
≥98%
Allosteric inhibitor of Bax channel activation
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