BARD1 Products
The BARD1 (BRCA1-associated RING Domain 1) protein forms a heterodimeric complex with BRCA1. BARD1-bound BRCA1 is stabilized and recruited to the nucleus where the complex acts as a Ubiquitin E3 Ligase to function in DNA repair or cell survival pathways. One target of the BRCA1/BARD1 E3 Ligase activity, RNA Polymerase II, is degraded and subsequent transcription and RNA processing are inhibited. This allows time for repair of damaged DNA before cellular events progress.
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37 results for "BARD1" in Products
37 results for "BARD1" in Products
BARD1 Products
The BARD1 (BRCA1-associated RING Domain 1) protein forms a heterodimeric complex with BRCA1. BARD1-bound BRCA1 is stabilized and recruited to the nucleus where the complex acts as a Ubiquitin E3 Ligase to function in DNA repair or cell survival pathways. One target of the BRCA1/BARD1 E3 Ligase activity, RNA Polymerase II, is degraded and subsequent transcription and RNA processing are inhibited. This allows time for repair of damaged DNA before cellular events progress.
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2A11 |
| Applications: | ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |