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Bad: Proteome Profiler Antibody Arrays

The Bcl-2 family of proteins consists of both inhibitors and promoters of apoptosis. The relative ratios of pro- and anti-apoptotic Bcl-2 family proteins determine the sensitivity or resistance of cells to a variety of apoptotic signals. The pro-apoptoptic Bad (Bcl-2-antagonist of cell death) heterodimerizes strongly with Bcl-x, less strongly with Bcl-2, and not at all with Bax, Bcl-xS, Mcl-1, A1, or itself. When Bad dimerizes with Bcl-xL, Bax is displaced and its apoptosis-inducing ability is restored.

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2 results for "Bad Proteome Profiler Antibody Arrays" in Products

2 results for "Bad Proteome Profiler Antibody Arrays" in Products

Bad: Proteome Profiler Antibody Arrays

The Bcl-2 family of proteins consists of both inhibitors and promoters of apoptosis. The relative ratios of pro- and anti-apoptotic Bcl-2 family proteins determine the sensitivity or resistance of cells to a variety of apoptotic signals. The pro-apoptoptic Bad (Bcl-2-antagonist of cell death) heterodimerizes strongly with Bcl-x, less strongly with Bcl-2, and not at all with Bax, Bcl-xS, Mcl-1, A1, or itself. When Bad dimerizes with Bcl-xL, Bax is displaced and its apoptosis-inducing ability is restored.

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Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies

Contains 8 membranes - each spotted in duplicate with 21 different apoptosis antibodies

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