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230 results for "BACE-1" in Products

BACE-1 Products

Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.

Source: NS0
Accession #: P56817.1
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes

BACE1 and BACE2 inhibitor

Chemical Name: N-[3-[(5R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
Purity: ≥98% (HPLC)
BACE1 and BACE2 inhibitor

Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies

Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 Monoclonal Clone #3C1C3
Applications: WB, ELISA, ICC/IF, Flow, CyTOF-ready
Western Blot: BACE-1 Antibody (3C1C3)BSA Free [NBP2-37261]
(6)
Assay Range: 0.625 - 40 ng/mL
Applications: ELISA
Human BACE-1 ELISA Standard Curve

Potent and selective β-secretase (BACE) inhibitor

Chemical Name: N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide hydrochloride
Purity: ≥98% (HPLC)
Potent and selective β-secretase (BACE) inhibitor
Source: NS0
Accession #: P56818
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes
Applications: ELISA
Human BACE-1 ELISA Kit (Chemiluminescence)
(2)
Reactivity: Human, Rat
Details: Mouse IgG1 kappa Monoclonal Clone #2C1
Applications: IHC, WB, ELISA, Func
Western Blot: BACE-1 Antibody (2C1) [H00023621-M01]
(5)
Reactivity: Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Western Blot: BACE-1 Antibody [NBP3-13390]
(3)
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