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255 results for "B-Raf" in Products

B-Raf Products

The Raf serine/threonine kinases are effectors of Ras that function as MAP3Ks in the ERK phosphorylation cascade. Mammals express three Raf proteins: Raf-1 (C-Raf); A-Raf; and B-Raf, strongly expressed in fetal brain and adult cerebrum. Mice with a targeted disruption of the B-raf gene die of vascular defects during mid-gestation. B-raf mutations have been found in two-thirds of malignant melanomas, with the single substitution V599E in the kinase domain the most frequent occurrence.

Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, Simple Western
Immunohistochemistry-Paraffin: B-Raf Antibody [NBP1-89942]
(10)
Reactivity:
Human, Mouse, Rat, Monkey
Details:
Mouse IgG1 Monoclonal Clone #OTI5A9
Applications:
IHC, WB, Flow, ICC/IF, IP
Western Blot: B-Raf Antibody (OTI5A9) [NBP1-47668]
(11)
Reactivity:
Human, Mouse, Rat, Monkey
Details:
Mouse IgG1 Monoclonal Clone #OTI5A9
Applications:
IHC, WB, Flow, ICC/IF, IP, + 1 More
Western Blot: B-Raf Antibody (OTI5A9)Azide and BSA Free [NBP2-70260]
(11)

Potent B-Raf inhibitor

Chemical Name:
2,3-Dihydro-5-[1-(2-hydroxyethyl)-3-(4-pyridinyl)-1H-pyrazol-4-yl]-1H-inden-1-one oxime
Purity:
≥98%
Potent B-Raf inhibitor

Potent B-Raf inhibitor

Chemical Name:
5-[2-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2,3-dihydro-1H-inden-1-one oxime
Purity:
≥98%
Potent B-Raf inhibitor
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Simple Western
Detection of Human B-Raf antibody by Western Blot.
(4)

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #RM8
Applications:
IHC, WB, ELISA, ICC/IF
(4)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, IP
Immunohistochemistry-Paraffin: B-Raf Antibody [NBP2-15531]
(6)
Reactivity:
Human
Details:
Mouse IgG2b Kappa Monoclonal Clone #IHC600
Applications:
IHC
Immunohistochemistry-Paraffin: B-Raf Antibody (IHC600) - V600-E Mutation [NBP3-00517]
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG2A Monoclonal Clone #336016
Applications:
WB
Detection of Human/Mouse/Rat B‑Raf antibody by Western Blot.
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #CL4003
Applications:
IHC, WB
Western Blot: B-Raf Antibody (CL4003) [NBP2-59034]
(5)
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #CL4004
Applications:
IHC, WB
Western Blot: B-Raf Antibody (CL4004) [NBP2-59035]
(5)
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA, ICC/IF
Western Blot: B-Raf AntibodyBSA Free [NBP2-41219]
(4)
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #CL4003
Applications:
IHC, WB
B-Raf Antibody (CL4003) - Azide and BSA Free Immunohistochemistry-Paraffin: B-Raf Antibody [NBP3-44117]
(5)
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #CL4004
Applications:
IHC, WB
B-Raf Antibody (CL4004) - Azide and BSA Free Immunohistochemistry-Paraffin: B-Raf Antibody [NBP3-44118]
(5)
Reactivity:
Human, Mouse
Details:
Mouse IgG1 Monoclonal Clone #1H12
Applications:
IHC, WB, ELISA, ICC/IF
Western Blot: B-Raf Antibody (1H12)BSA Free [NBP1-47433]
(3)
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #1H12F1
Applications:
IHC, WB, ELISA
Western Blot: B-Raf Antibody (1H12F1)BSA Free [NBP1-47555]
(4)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #23GB3960
Applications:
WB, Flow, ICC/IF
B-Raf [p Thr401] Antibody (23GB3960)
(3)
Reactivity:
Human
Source:
Sf 21 (baculovirus)
Applications:
Enzyme Activity
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF
Western Blot: B-Raf Antibody [NBP2-58818]
(2)

Potent Raf kinase inhibitor

Chemical Name:
3-(1-Cyano-1-methylethyl)-N-[3-[(3,4-dihydro-3-methyl-4-oxo-6-quinazolinyl)amino]-4-methylphenyl]benzamide
Purity:
≥98%
Potent Raf kinase inhibitor

PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor

Chemical Name:
2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
Purity:
≥98%
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor

Potent and selective B-Raf, CDK16 and NEK9 inhibitor; anticancer; also targets human proteins in the SARS-CoV-2 interactome

Chemical Name:
N-[3-[5-(2-Aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide methanesulfonate
Purity:
≥98%
Potent and selective B-Raf, CDK16 and NEK9 inhibitor; anticancer; also targets human proteins in the SARS-CoV-2 interactome

Potent and selective B-Raf, CDK16 and NEK9 inhibitor; anticancer; also targets human proteins in the SARS-CoV-2 interactome

Chemical Name:
N-[3-[5-(2-Aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide methanesulfonate
Purity:
≥98%
Potent and selective B-Raf, CDK16 and NEK9 inhibitor; anticancer; also targets human proteins in the SARS-CoV-2 interactome

Selective BRAF-V600E protein Degrader (uSMITE™)

Chemical Name:
N-[[4-[3-[2,6-Difluoro-3-[(propylsulfonyl)amino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]methyl]-5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]pentanamide
Purity:
≥98%
Selective BRAF-V600E protein Degrader (uSMITE™)
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