7 results for "ALK Inhibitors Small Molecules and Peptides" in Products
ALK Inhibitors: Small Molecules and Peptides
Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor
| Chemical Name: | N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine |
| Purity: | ≥98% (HPLC) |
Potent c-MET/ALK inhibitor
| Alternate Names: | PF 02341066,PF 2341066 |
| Chemical Name: | 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine |
| Purity: | ≥98% (HPLC) |
Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
| Alternate Names: | LDK378 |
| Chemical Name: | 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% (HPLC) |
Potent and selective ALK1/2 inhibitor. Brain-penetrant
| Chemical Name: | 6-(4-Piperazin-1-ylphenyl)-3-quinolin-4-ylfuro[3,2-b]pyridine trihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective ALK2 inhibitor
| Chemical Name: | 1-[4-[5-(4-Fluoro-3,5-dimethoxyphenyl)-4-methyl-3-pyridinyl]phenyl]piperazine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
| Chemical Name: | 2-[[2-[[1-[(Dimethylamino)ethanoyl]-5-(methyloxy)-2,3-dihydro-1H-indol-6-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-6-fluoro-N-methylbenzamide |
| Purity: | ≥98% (HPLC) |
A 83-01 synthesized to Ancillary Material Grade
| Chemical Name: | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide |
| Purity: | ≥98% |
