WRW4

Tocris Bioscience, part of Bio-Techne | Catalog # 2262

Selective FPR2 antagonist
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Key Product Details

Description

Selective FPR2 antagonist

Alternative Names

WRW4

View all Formyl Peptide Receptor Antagonists »

Product Description

WRW4 is a selective antagonist of formyl peptide receptor 2 (FPR2) signaling. Inhibits WKYMVm binding to FPR2 (IC50 = 0.23 μM) and inhibits intracellular calcium release induced by WKYMVm, MMK 1, amyloid β42, and F peptide. Also inhibits FPR2-mediated signaling in human neutrophils; blocks chemotactic migration and superoxide generation by amyloid β42 peptide.

Product Specifications

Molecular Weight

1104.28

Formula

C61H65N15O6

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

878557-55-2

PubChem ID

49768327

InChI Key

IRJDOVLLPORVJP-WOAIKHIASA-N

SMILES

[H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product.

Product Documents for WRW4

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for WRW4

For research use only

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