Formyl Peptide Receptor Antagonists Products

The formyl peptide receptor family, FPR1, FPR2 and FPR3 (formerly FPR, FPRL1 and FPRL2 respectively) are G_i-protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes and found at lower expression levels on endothelial cells, neurons, astrocytes and hepatocytes.

Formyl peptide receptors are involved in antibacterial host defence and inflammation. Activation of FPRs mediates induction of neutrophil chemotaxis and stimulation of the degranulation of neutrophils. In ...