VU 0071063

Name: VU 0071063
Brand: Tocris Bioscience
SKU: 7057

Tocris Bioscience, part of Bio-Techne | Catalog # 7057

COA / SDS

Selective activator of SUR1 Kir6.2 channels

Key Product Details

Chemical Name:	7-[[4-(1,1-Dimethylethyl)phenyl]methyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
Purity:	≥98%

View Full Technical Details for VU 0071063

Technical Data
Citations

Biological Activity for VU 0071063

VU 0071063 is a selective activator of SUR1 K_ir6.2 channels and pancreatic β-cell K_ATP channels (EC₅₀ = 7 μM and 0.3-10.3 μM, respectively). VU 0071063 inhibits insulin secretion in pancreatic β-cells by inducing hyperpolarization of β-cell membranes and reduces voltage-dependent calcium channel activation and Ca²⁺ influx. VU 0071063 is active in vivo and brain penetrant.

Technical Data for VU 0071063

Formula	C₁₈H₂₂N₄O₂
Storage	Store at -20°C
Purity	≥98%
CAS Number	333415-38-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for VU 0071063

Solubility

Soluble Soluble to 5 mM in DMSO

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Product Documents for VU 0071063

COA

Certificate of Analysis

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