trans-Triprolidine hydrochloride

Name: trans -Triprolidine hydrochloride
Brand: tocris
SKU: 0662

Catalog # 0662

Citations (2)

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Key Product Details

Description:	Highly potent H₁ antagonist
Chemical Name:	(E)-2-[1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	314.86

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Biological Activity

Potent H₁ receptor antagonist.

Technical Data

M. Wt	314.86
Formula	C₁₉H₂₂N₂.HCl
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	550-70-9
PubChem ID	5702129
InChi Key	WYUYEJNGHIOFOC-NWBUNABESA-N
Smiles	Cl[H].CC1=CC=C(C=C1)C(=C/CN1CCCC1)\C1=CC=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	31.49	100

Preparing Stock Solutions

The following data is based on the product molecular weight 314.86.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.18 mL	15.88 mL	31.76 mL
5 mM	0.64 mL	3.18 mL	6.35 mL
10 mM	0.32 mL	1.59 mL	3.18 mL
50 mM	0.06 mL	0.32 mL	0.64 mL

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References

References are publications that support the biological activity of the product.

Hill Distribution properties and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 1990 PMID: 2164693
Merck Index

Citations (2)

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Citations are publications that use Bio-Techne products. Selected citations for trans-Triprolidine hydrochloride include:

Femenia et al. (2015) Hippocampal-Dependent Antidepressant Action of the H3 Receptor Antagonist Clobenpropit in a Rat Model of Depression. Int J Neuropsychopharmacol. 18
PMID: 25762718
Kwiatkowski et al. (2013) Coordination of distinct but interacting rhythmic motor programs by a modulatory projection neuron using different co-transmitters in different ganglia. J Exp Biol. 216:1827
PMID: 23393282

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Product Datasheets

COA

Certificate of Analysis

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trans-Triprolidine hydrochloride

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Key Product Details

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Biological Activity

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References

Citations (2)

Product Datasheets

COA

Certificate of Analysis

SDS

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