Toyocamycin

Tocris Bioscience, part of Bio-Techne | Catalog # 5270

Adenosine analog; antifungal antibiotic
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Key Product Details

Description

Adenosine analog; antifungal antibiotic

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Product Description

Toyocamycin is an adenosine analog; antifungal antibiotic. Inhibits RNA self-cleavage in HEK79 cells and PI 3-kinase activity in A431 epidermoid carcinoma cell membrane fractions. Also inhibits thapsigargin-induced XBP1-luciferase activation and induces apoptosis in multiple myeloma cell lines.

Product Specifications

Molecular Weight

291.26

Formula

C12H13N5O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

CAS Number

606-58-6

PubChem ID

12444444

InChI Key

XOKJUSAYZUAMGJ-NNXMZFEESA-N

SMILES

NC1=C2C(N([C@@H]3O[C@H](CO)[C@H](O)[C@@H]3O)C=C2C#N)=NC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 29.13 100

Preparing Stock Solutions for Toyocamycin

The following data is based on the product molecular weight 291.26

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.43 mL 17.17 mL 34.33 mL
5 mM 0.69 mL 3.43 mL 6.87 mL
10 mM 0.34 mL 1.72 mL 3.43 mL
50 mM 0.07 mL 0.34 mL 0.69 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Toyocamycin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Toyocamycin

For research use only

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