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TC E3 5032

Tocris Bioscience, part of Bio-Techne | Catalog # 6628

Precursor to Pomalidomide-based PROTACs
Discontinued Product
6628 has been discontinued. View all Degrader Building Blocks products.

Key Product Details

Description

Precursor to Pomalidomide-based PROTACs

Product Description

TC E3 5032 is a functionalized cereblon ligand for PROTAC® research and development. Precursor to Pomalidomide (Cat.No. 6302) -based PROTACs. Incorporates a fluoro leaving group to allow conjugation to amine linker. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications

Molecular Weight

276.22

Formula

C13H9FN2O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione

CAS Number

835616-60-9

PubChem ID

11859051

InChI Key

CRAUTELYXAAAPW-UHFFFAOYSA-N

SMILES

O=C(C1=C(C=CC=C1C2=O)F)N2C3CCC(NC3=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Calculators

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Product Documents for TC E3 5032

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TC E3 5032

For research use only

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