Tamoxifen

Name: Tamoxifen
Brand: Tocris Bioscience
SKU: 6342
Rating: 5 (1 reviews)

Tocris Bioscience a Bio-Techne Brand

Catalog # 6342

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(1)

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Key Product Details

Description:	Estrogen receptor partial agonist/antagonist
Chemical Name:	2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethylethanamine
Purity:	≥99% (HPLC)
Molecular Weight:	371.51

View Full Technical Details for Tamoxifen

Biological Activity for Tamoxifen

Tamoxifen is a selective estrogen receptor modulator (SERM). Exhibits antiestrogenic effects in mammary tissue and estrogen-like effects in bone. Anticancer. Tamoxifen citrate (Cat.No. 0999) is also available.

Compound Libraries for Tamoxifen

Tamoxifen is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for Tamoxifen

M. Wt	371.51
Formula	C₂₆H₂₉NO
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	10540-29-1
PubChem ID	2733526
InChi Key	NKANXQFJJICGDU-QPLCGJKRSA-N
Smiles	CN(C)CCOC1=CC=C(C=C1)/C(C2=CC=CC=C2)=C(CC)\C3=CC=CC=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Tamoxifen

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	37.15	100
	DMSO	7.43	20

Preparing Stock Solutions for Tamoxifen

The following data is based on the product molecular weight 371.51.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.69 mL	13.46 mL	26.92 mL
5 mM	0.54 mL	2.69 mL	5.38 mL
10 mM	0.27 mL	1.35 mL	2.69 mL
50 mM	0.05 mL	0.27 mL	0.54 mL

Molarity Calculator

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Reconstitution Calculator

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References for Tamoxifen

References are publications that support the biological activity of the product.

Jordan Tamoxifen: a most unlikely pioneering medicine. Nat.Rev.Drug Discov. 2003 PMID: 12612646

Citations for Tamoxifen (1)

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Citations are publications that use Bio-Techne products. Selected citations for Tamoxifen include:

Silva et al. (2019) Study of the Combination of Self-Activating Photodynamic Therapy and Chemotherapy for Cancer Treatment. Biomolecules. 9
PMID: 31434290

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Tamoxifen for ERT-cre mice

Name: Anonymous

Species: Mouse

Assay Type: In Vivo

given for tamoxifen-inducible cre mice. saw excellent GFP expression with 2 doses.

given 180mg/kg/day i.p., injections 24 hours apart. dissolved 30mg/ml in 1:9 etoh and sunflower seed oil

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Product Documents for Tamoxifen

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

SDS

⚠ WARNING: This product can expose you to chemicals including Tamoxifen and its salts, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov