RuBi-Glutamate

Name: RuBi-Glutamate
Brand: Tocris Bioscience
SKU: 3574
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3574

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Citations (24)

COA / SDS

Caged glutamate; excited by visible wavelengths

Key Product Details

Description:	Caged glutamate; excited by visible wavelengths
Chemical Name:	(bis(2,2'-Bipyridine-N,N')trimethylphosphine)-(S)-1-aminopropane-1,3-dicarboxylic acid ruthenium(2⁺) complex sodium hexafluorophosphate salt
Molecular Weight:	970.54

View Full Technical Details for RuBi-Glutamate

Technical Data
Citations / Reviews (1)

Biological Activity for RuBi-Glutamate

RuBi-Glutamate is a ruthenium-bipyridine-trimethylphosphine caged glutamate that can be excited by visible wavelengths and releases glutamate after one- or two-photon excitation. Has high quantum efficiency and can be used at low concentrations, partly avoiding blockade of GABAergic transmission seen with other caged glutamate compounds. Displays high spatial resolution and generates excitatory responses in individual dendritic spines with physiological kinetics.

MNI-caged-L-glutamate (Cat. No. 1490) also available.

Licensing Information

Sold under licence from Columbia University

Technical Data for RuBi-Glutamate

M. Wt	970.54
Formula	C₂₈H₃₂N₅O₄PRu.2NaPF₆
Storage	Store at -20°C
CAS Number	2417096-44-5
PubChem ID	90488860
InChi Key	SQQVSHWHIPVYSZ-UHFFFAOYSA-L
Smiles	[Na+].[Na+].[Ru++].CP(C)C.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F.NC(CCC([O-])=O)C([O-])=O.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CN=C(C=C1)C1=CC=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for RuBi-Glutamate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	19.41	20

Preparing Stock Solutions for RuBi-Glutamate

The following data is based on the product molecular weight 970.54.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	5.15 mL	25.76 mL	51.52 mL
1 mM	1.03 mL	5.15 mL	10.30 mL
2 mM	0.52 mL	2.58 mL	5.15 mL
10 mM	0.10 mL	0.52 mL	1.03 mL

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Reconstitution Calculator

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References for RuBi-Glutamate

References are publications that support the biological activity of the product.

Salierno A fast ruthenium polypyridine cage complex photoreleases glutamate with visible or IR light in one and two photon regimes. J.Inorg.Biochem. 2010 PMID: 20060592
Fino RuBi-Glutamate: two-photon and visible-light photoactivation of neurons and dendritic spines. Front.Neural Circuits 2009 PMID: 19506708